Glossary

Apolipoprotein E (APOE): protein normally present in the body in three forms: 2, 3 and 4. APOE 4 represents a risk factor for Alzheimer’s disease.

Beta amyloid protein: one of the two abnormal proteins that may accumulate in the brain and may cause Alzheimer’s disease. It is the main constituent of the amyloid plaque, one of the two lesions characteristic of Alzheimer’s disease.

Biomarker: A biomarker is a measurable biological characteristic related to the normal aging process or not.

CMRR: Resources and Research Memory Center. 

Cognitive pathology: pathology affecting cognitive function (memory, language, orientation…).

CTAD: Clinical Trial in Alzheimer’s Disease conference.

EADC: European Alzheimer’s Disease Consortium.

EHPAD: Home for dependent seniors.

Endowment fund: An endowment fund is a financial asset, typically held by a non-profit organization that receives and manages all types of investments and uses the funds to financially support the general interest of the mission according to the will of its founders and donors.

Hyperphosphorylated Tau protein: one of the two abnormal proteins that may accumulate in the brain and that may cause of Alzheimer’s disease. It is the main constituent of neurofibrillary degeneration one of the two lesions characteristic of Alzheimer’s disease.

IAGG: International Association of Gerontology and Geriatrics.

ICFSR: International Conference for Frailty and Sarcopenia Research.

ICOPE: Integrated care for seniors.

INSPIRE: Prevention, Healthy Aging and Rejuvenating Medicine Institute.

JPAD: the Journal of Prevention of Alzheimer’s Disease.

NGO: Non Governmental Organization.

Neurofibrillary degeneration: intra-neuronal lesion characteristic of Alzheimer’s disease and consisting essentially of hyperphosphotylated Tau protein.

Proteinopathy: secondary illness to the deposition in the brain of abnormal protein.

Rejuvenative Medicine: Medicine aimed to reduce specific effects of aging.

Vascular risks: high blood pressure, high cholesterol, diabetes, obesity, smoking…

WHO: World Health Organization.